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. 2015 Jan 12;112(4):1155–1160. doi: 10.1073/pnas.1412833112

Fig. 1.

Fig. 1.

Demonstration of the Hp typing methods used, showing examples of both the aSAH patients and longitudinal controls of known Hp type that were incorporated in all Hp typing of patients. (A) Hp genotyping of control DNA samples. Lanes 1 and 12 show DNA ladders; lanes 3, 5, 7, 8, and 11 show the Hp1-1 genotype; lanes 2, 6, and 9 show the Hp2-1 genotype; and lanes 4 and 10 show the Hp2-2 genotype. The bands corresponding to Hp1 and Hp2 were subsequently confirmed to be specific by restriction enzyme analysis. (B) Hp phenotyping of serum samples from controls and aSAH patients. Lane 1 shows a molecular weight marker; lanes 3, 5, 6, and 8 show the Hp 1–1 phenotype; lanes 2 and 9 show Hp 2–1 individuals; and lanes 4 and 7 show the Hp2-2 phenotype. The controls in lanes 2–4 correspond to the same controls in lanes 2–4 in A, demonstrating the matching Hp types between the two methods.