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. 2015 Jan 12;112(4):1131–1136. doi: 10.1073/pnas.1424012112

Table 2.

Time-dependent and time-independent gene signatures of MCF-10A-H1047R

Gene set* No. of genes 0 h 24 h
NES P NES P
SMID BREAST CANCER BASAL UP 412 1.58 0 1.45 0
SMID BREAST CANCER BASAL DN 391 −1.18 0.043 −1.04 0.333
ONDER CDH1 TARGETS 2 DN§ 390 2.5 0 1.79 0
ONDER CDH1 TARGETS 2 UP 155 −1.67 0 −2.29 0
REACTOME CELL CYCLE# 355 −1.98 0 1.56 0
KAUFFMANN DNA REPAIR GENESǁ 211 −1.57 0 1.72 0
DANG REGULATED BY MYC UP** 64 −1.75 0 1.05 0.363
DANG REGULATED BY MYC DN†† 185 1.36 0.017 −1.91 0
ZWANG CLASS 2 TRANSIENTLY INDUCED BY EGF‡‡ 33 1.78 0.01 −2.17 0
*

As listed in the MSigDB (www.broadinstitute.org/gsea/msigdb).

Genes up-regulated in the basal subtype of breast cancer (36).

Genes down-regulated in the basal subtype of breast cancer (36).

§

Genes down-regulated after E-cadherin knock-down (38).

Genes up-regulated after E-cadherin knock-down (38).

#

Available at www.reactome.org.

ǁ

Genes involved in DNA repair (39).

**

Genes up-regulated by Myc (40).

††

Genes down-regulated by Myc (40).

‡‡

Genes transiently induced by EGF (37).