Table 2.

Top 10 genes for BMI identified by T5-rob in the analysis of the WHI data

					P value
Gene	Accession	Chr	m	Rsq	T5-rob	T5-std	T5-seq
ODF2L	NM_020729	1	11	0.685	$3.1\times {10}^{-5}$	$1.7\times {10}^{-5}$	$4.9\times {10}^{-2}$
ITSN1	NM_003024	21	7	0.609	$5.0\times {10}^{-5}$	$3.3\times {10}^{-5}$	$3.3\times {10}^{-2}$
KDM6B	NM_001080424	17	30	0.266	$5.8\times {10}^{-5}$	$1.0\times {10}^{-5}$	$6.7\times {10}^{-2}$
SOCS1	NM_003745	16	2	0.348	$7.8\times {10}^{-5}$	$1.6\times {10}^{-5}$	$1.5\times {10}^{-2}$
ODF2L	NM_001007022	1	9	0.689	$1.1\times {10}^{-4}$	$7.1\times {10}^{-5}$	$6.4\times {10}^{-2}$
ACADVL	NM_000018	17	15	0.189	$1.6\times {10}^{-4}$	$6.8\times {10}^{-5}$	$1.1\times {10}^{-1}$
BDNF	NM_170734	11	2	0.628	$2.1\times {10}^{-4}$	$2.5\times {10}^{-4}$	$1.0\times {10}^{-1}$
TRDMT1	NM_004412	10	3	0.718	$2.3\times {10}^{-4}$	$1.8\times {10}^{-4}$	$8.1\times {10}^{-2}$
FAM60A	NM_001135811	12	1	0.768	$2.3\times {10}^{-4}$	$4.0\times {10}^{-4}$	$6.5\times {10}^{-1}$
PDGFRA	NM_006206	4	12	0.563	$2.4\times {10}^{-4}$	$2.2\times {10}^{-4}$	$1.4\times {10}^{-3}$

Chr is the chromosome number, m is the number of variants in the gene, and Rsq is the Rsq value averaged over the variant sites in the gene. T5-rob and T5-std are the T5 tests in the integrative analysis of sequencing and GWAS data with the robust and standard variance estimators, respectively, and T5-seq is the T5 test using only sequenced subjects.