Table 1.
Correlation between clinical parameters and LSD1 expression level in esophageal cancer tissues
| Clinical parameters | Cases | LSD1 immunostaining | P-value | ||
|---|---|---|---|---|---|
|
| |||||
| H-score ≤ 235 | H-score > 235 | χ2 | |||
| Gender | |||||
| Male | 75 | 65 (86.7%) | 10 (13.3%) | 0.016 | 0.900 |
| Female | 28 | 24 (85.7%) | 4 (14.3%) | ||
| Age (years) | |||||
| < 60 | 63 | 55 (87.3%) | 8 (12.7%) | 0.110 | 0.740 |
| ≥ 60 | 40 | 34 (85.0%) | 6 (15.0%) | ||
| Tumor size (cm) | |||||
| < 3.5 | 38 | 37 (97.4%) | 1 (0.6%) | 6.159 | 0.013 |
| ≥ 3.5 | 65 | 52 (83.9%) | 13 (16.1%) | ||
| Tumor invasion depth (T) | |||||
| T1 + T2 | 59 | 53 (89.8%) | 6 (10.2%) | 1.378 | 0.241 |
| T3 + T4 | 44 | 36 (81.8%) | 8 (18.2%) | ||
| Nodal metastasis (N) | |||||
| Yes | 49 | 37 (75.5%) | 12 (24.5%) | 9.450 | 0.002 |
| No | 54 | 52 (96.3%) | 2 (3.7%) | ||
| Distant metastasis (M) | |||||
| Yes | 16 | 11 (68.8%) | 5 (31.2%) | 5.029 | 0.025 |
| No | 87 | 78 (89.7%) | 9 (10.3%) | ||
| TNM stage* | |||||
| I | 13 | 13 (100.0%) | 0 (0.0%) | 6.621 | 0.010 |
| II | 56 | 50 (89.3%) | 6 (10.7%) | ||
| III | 18 | 15 (83.3%) | 3 (16.7%) | ||
| IV | 16 | 11 (68.8%) | 5 (31.2%) | ||
Values in bold signify P < 0.05.
*
Chi-square test for trend.