Table 2.
The genotype distributions and allele frequencies of the studied polymorphisms between patients and controls, and their risk prediction for CD under three genetic models of inheritance
| Polymorphism | Patients (N = 312) | Controls (N = 479) | P χ2 | Genetic models | OR; 95% CI |
|---|---|---|---|---|---|
| rs17855750 | |||||
| TT | 242 | 393 | Additive | 1.31; 0.95-1.80 | |
| GT | 64 | 81 | 0.090 | Dominant | 1.32; 0.93-1.88 |
| GG | 6 | 5 | Recessive | 1.86; 0.56-6.14 | |
| G (%) | 12.2 | 9.5 | 0.24 | ||
| rs153109 | |||||
| AA | 92 | 181 | Additive | 1.26; 1.02-1.56 | |
| GA | 170 | 232 | 0.055 | Dominant | 1.45; 1.07-1.97 |
| GG | 50 | 66 | Recessive | 1.19; 0.08-1.78 | |
| G (%) | 43.3 | 38.0 | 0.036 | ||
| rs181206 | |||||
| TT | 240 | 361 | Additive | 0.93; 0.68, 1.27 | |
| CT | 68 | 112 | 0.92 | Dominant | 0.92; 0.66, 1.28 |
| CC | 4 | 6 | Recessive | 1.02; 0.29, 3.66 | |
| C (%) | 12.2 | 12.9 | 0.65 |
Abbreviations: OR, odds ratio; 95% CI, 95% confidence interval.