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PD prevented pulmonary microvascular permeability, edema and dysfunction. Increased EB and W/D values, decreased PaO2/FIO2 were detected in the LPS + NS group, which were improved by medium and large dose of PD treatment. A. Evans blue (EB) content in lungs. B. Wet-to-dry (W⁄D) lung weight ratio. C. Oxygenation index (PaO2/FIO2). Data are presented as mean ± SD (n = 6 in each group). *P < 0.05 vs. sham group; #P < 0.05 vs. LPS + NS group.
