Table 2.
Characteristics of studies included in this meta-analysis
| Author | Year | Country | Ethnicity | Genotyping methods | Sample size (case/control) | Case | Control | Quality score | P HWE | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|||||||||||||
| Val/Val | Val/Met | Met/Met | Val/Val | Val/Met | Met/Met | ||||||||
| Gursoy | 2003 | Turkey | Caucasian | PCR-RFLP | 61/61 | 16 | 33 | 12 | 29 | 22 | 10 | 8 | 0.116 |
| Gilberto | 2007 | Spain | Caucasian | Taqman | 78/80 | 29 | 40 | 9 | 19 | 39 | 22 | 9 | 0.833 |
| Gilberto | 2007 | Mexico | Mixed | Taqman | 57/53 | 23 | 32 | 2 | 15 | 14 | 4 | 9 | 0.794 |
| Tander | 2008 | Turkey | Caucasian | PCR-RFLP | 80/91 | 26 | 32 | 22 | 30 | 34 | 27 | 9 | 0.016 |
| Potvin | 2009 | Cannda | Caucasian | PCR-RFLP | 37/36 | 8 | 23 | 6 | 9 | 21 | 6 | 7 | 0.294 |
| Matsuda | 2010 | Brazil | Mixed | PCR-RFLP | 51/51 | 9 | 23 | 19 | 15 | 31 | 5 | 7 | 0.059 |
| Martinez | 2012 | Spain | Caucasian | Taqman | 113/65 | 34 | 52 | 27 | 17 | 43 | 5 | 10 | 0.003 |
| Barbosa | 2012 | Brazil | Mixed | PCR-RFLP | 112/110 | 9 | 16 | 87 | 50 | 29 | 31 | 6 | < 0.001 |
PCR-RFLP: Polymerase Chain Reaction-restriction Fragment Length Polymorphism; HWE: Hardy-Weinberg Equilibrium.