Table 1.
Associations of combined miR-23a and miR-23b expression with the clinicopathological features of gastric cancer (GC)
| Clinical features | Case Number (%) | miR-23a-high/miR-23b-high | |
|---|---|---|---|
|
| |||
| (N, %) | P | ||
| Age (years) | |||
| < 58 | 50 (31.25) | 20 (40.00) | NS |
| ≥ 58 | 110 (68.75) | 40 (36.36) | |
| Gender | |||
| Male | 108 (67.50) | 42 (38.89) | NS |
| Female | 52 (32.50) | 18 (34.62) | |
| Tumor size (cm) | |||
| < 4 | 58 (36.25) | 20 (34.48) | NS |
| ≥ 4 | 102 (63.75) | 40 (39.22) | |
| Lauren classification | |||
| Diffuse type | 99 (61.88) | 35 (35.35) | NS |
| Intestinal type | 61 (38.12) | 25 (40.98) | |
| Differentiation | |||
| Well or moderate | 58 (36.25) | 22 (37.93) | NS |
| Poor | 102 (63.75) | 38 (37.25) | |
| Lymph node metastasis | |||
| Negative | 100 (62.50) | 20 (20.00) | 0.008 |
| Positive | 60 (37.50) | 40 (66.67) | |
| TNM stage | |||
| I | 16 (10.00) | 0 (0.00) | < 0.001 |
| II | 40 (25.00) | 6 (15.00) | |
| III | 42 (26.25) | 15 (35.71) | |
| IV | 62 (38.75) | 39 (62.90) | |
| Depth of invasion | |||
| Mucosa or submucosa | 26 (16.25) | 1 (3.85) | 0.02 |
| Muscularis or subserosa | 20 (12.50) | 3 (15.00) | |
| Serosa | 82 (51.25) | 35 (42.68) | |
| Adjacent structure | 32 (20.00) | 21 (65.63) | |
Note: ‘NS’ refers to the difference without statistical significance.