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. 2014 Dec 1;172(4):1034–1044. doi: 10.1111/bph.12963

Figure 2.

Figure 2

Long-lasting mechanical allodynia after sciatic nerve injury in KOP+/+ and KOP−/− mice. Unilateral cuffing of the main branch of the sciatic nerve induced long-lasting mechanical allodynia, as tested using von Frey filaments. (A) Insertion of the cuff did not affect the mechanical threshold of the contralateral paw (left paw). (B) The cuff induced an ipsilateral (right paw) mechanical allodynia in both KOP+/+ and KOP−/− mice. Data are expressed as mean ± SEM, n (number of animals) are given in parentheses.