Effects of ondansetron (Ond; 1 mg·kg−1) on mRNA expression of inflammatory mediators in the muscle layer of intestine from POI mice. Messenger RNA levels of CCL2, IL-1β, IL-6, TNF-α, IL-10 and iNOS (A–F). Data shown are means ±SEM from four independent experiments. *P < 0.05, **P < 0.01; significantly different from control. #P < 0.05, ##P < 0.01; significantly different from POI.