Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dose Reduction by Pre-Existing Organ Function and Imatinib Dose
| Imatinib | Organ Function | Dose Reduction, No. (%) | P a |
|---|---|---|---|
| 400 mg | Renal dysfunction (n=4) | 2 (50) | .14 |
| Liver dysfunction (n=7) | 2 (29) | .20 | |
| Normal (n=39) | 6 (15) | ||
| 800 mg | Renal dysfunction (n=7) | 6 (86) | .12 |
| Liver dysfunction (n=31) | 17 (55) | .56 | |
| Normal (n=171) | 85 (50) |
P value is compared with patients with normal organ function.
