Table 3.

Predictors of mortality after lung cancer resection

Variable	All Patients OR [95% CI]	P value	Males OR [95% CI]	P value	Females OR [95% CI]	P value
Female sex	0.56 [0.44, 0.71]	<0.001
Age	1.06 [1.04, 1.07]	<0.001	1.07 [1.08, 1.09]	<0.001	1.04 [1.02, 1.06]	<0.001
DLCO	0.98 [0.97, 0.98]	<0.001	0.98 [0.97, 0.99]	<0.001	0.97 [0.96, 0.98]	<0.001
Coronary Artery Disease	1.23 [0.97, 1.56]	0.095	1.09 [0.82, 1.45]	0.54	1.64 [1.05, 2.56]	0.035
Pre-operative Radiation Therapy	1.60 [1.05, 2.46]	0.033	1.86 [1.07, 3.25]	0.03	1.24 [0.64, 2.42]	0.53
Renal Insufficiency	3.13 [2.09, 4.68]	<0.001	2.80 [1.75, 4.49]	<0.001	4.68 [2.19, 10.04]	<0.001
Pathologic Stage		<0.001		0.007		0.048
I	1.00		1.00		1.00
II	1.05 [0.76, 1.44]		1.19 [0.82, 1.73]		0.79 [0.42, 1.49]
III	1.65 [1.24, 2.21]		1.65 [1.14, 2.38]		1.69 [1.04, 2.74]
IV	2.43 [1.46, 4.05]		2.53 [1.23, 4.77]		2.19 [0.91, 5.25]
Extent of Resection		<0.001		<0.001		<0.001
Sublobar	1.00		1.00		1.00
Lobar	1.53 [1.07, 2.19]		1.63 [1.03, 2.60]		1.41 [0.80, 2.48]
> Lobar	4.51 [2.95, 6.89]		4.81 [2.82,8.22]		4.44 [2.18, 9.05]
Approach		0.008				0.65
Thoracotomy	1.00		1.00	0.003	1.00
VATS	0.69 [0.52, 0.91]		0.58 [0.40, 0.85]		0.90 [0.58, 1.41]
Postoperative Air Leak > 5 days	1.33 [0.96, 1.84]	0.096	1.58 [1.08, 2.30]	0.023	0.88 [0.45, 1.71]	0.69
Postoperative Empyema	3.99 [1.88, 8.45]	0.002	3.82 [1.68, 8.65]	0.005	4.38 [0.55, 34.72]	0.25