TABLE 1.
Group Summary (mean ± sem)
| Group, method of study | Wt (g) | A1c (%) | n | With Mn2+? |
|---|---|---|---|---|
| WT, MRI | 30.5 ± 0.5 | 6.99 ± 0.19 | 6 | No |
| WT, MRI | 30.4 ± 0.4 | 7.0 ± 0.16 | 7 | Yes |
| STZ, MRI | 22.8 ± 0.6* | 13.2 ± 0.75* | 5 | Yes |
| WT, dark, IHC | 28 ± 1 | 6.03 ± 0.08 | 3 | No |
| WT, light, IHC | 27 ± 0.6 | 5.65 ± 0.23 | 3 | No |
| STZ, dark, IHC | 21 ± 1* | 12.92 ± 0.24* | 3 | No |
| STZ, light, IHC | 22 ± 0.3* | 13.33 ± 0.34* | 3 | No |
| WT, electrophysiology | 6.58 ± 0.41 | 3 | No | |
| STZ, electrophysiology | 14.11 ± 0.43* | 6 | No | |
| Arr1−/−, MRI | 17.3 ± 1.69 | 7 | Yes | |
| P48, MRI | 20.6 ± 0.75 | 5 | Yes |
A1c (%), % of hemoglobin that is glycated; WT, wild-type C57Bl/6J mouse; STZ, diabetic C57Bl/6J mouse; Arr1−/−, arrestin-1 null mouse; P48, Arr1+/+-P48 mouse.
*
P < 0.05 compared to WT data.