TABLE 2.
Rod response parameters from single-cell recordings
| Idark (pA) | I1/2 (phot μm−2) | Tpeak (ms) | Tintegr (ms) | τrec (ms) | |
|---|---|---|---|---|---|
| Control rods (n = 16) | 14.1 ± 0.9 | 18.1 ± 1.6 | 255 ± 12 | 554 ± 20 | 381 ± 16 |
| STZ rods (n = 16) | 13.9 ± 1.0 | 20.8 ± 3.8 | 189 ± 11 | 405 ± 37 | 284 ± 24 |
| t test | NS | NS | P < 0.0005 | P < 0.001 | P < 0.005 |
Experimental parameters: Idark, dark current measured from saturated responses; I1/2, half-saturating light intensity; time to peak (Tpeak) and integration time (Tintegr) refer to responses whose amplitudes were <0.2 Idark and fell within the linear range; τrec, time constant of single-exponential decay of dim flash response recovery phase. STZ, diabetic C57Bl/6J mouse. Values are means ± sem. NS indicates P > 0.05 between control and STZ diabetic rod values.