Table 2.
Prevalence of detectablea samples and geometric mean concentrations of AF-alb and UFB1 in children by village and sampling time.
| Sampling period | Nyabula | Kigwa | Kikelelwa | All villages | p-Valueb |
|---|---|---|---|---|---|
| AF-alb | |||||
| Recruitment | |||||
| Detectable [n (%)] | 23 (40) | 39 (95) | 36 (73) | 98 (67) | |
| Geometric mean (95% CI) (pg/mg) | 3.0 (2.1, 4.1) | 9.3 (7.0, 11.6) | 4.6 (3.4, 6.1) | 4.7 (3.9, 5.6) | < 0.001 |
| 6 months after recruitment | |||||
| Detectable [n (%)] | 53 (96) | 36 (97) | 33 (61) | 122 (84) | |
| Geometric mean (95% CI) (pg/mg) | 19.9 (13.5, 29.2) | 43.2 (28.7, 65.0) | 3.6 (2.8, 4.7) | 12.9 (9.9, 16.7) | < 0.001 |
| 12 months after recruitment | |||||
| Detectable [n (%)] | 53 (98) | 36 (100) | 53 (100) | 142 (99) | |
| Geometric mean (95% CI) (pg/mg) | 20.8 (16.2, 26.1) | 48.8 (34.5, 69.1) | 16.1 (12.6, 20.7) | 23.5 (19.9, 27.7) | < 0.001 |
| p-Valuec | < 0.001 | 0.011 | < 0.001 | < 0.001 | |
| UFB1 | |||||
| At recruitment | |||||
| Detectable [n (%)] | 61 (100) | 45 (100) | 51 (94) | 157 (98) | |
| Geometric mean (95% CI) (pg/mL) | 312.2 (230.0, 424.1) | 544.2 (397.2, 745.6) | 199.7 (137.7, 289.6) | 313.9 (257.4, 382.9) | < 0.001 |
| 6 months after recruitment | |||||
| Detectable [n (%)] | 56 (100) | 37 (100) | 48 (89) | 141 (96) | |
| Geometric mean (95% CI) (pg/mL) | 211.7 (161.1, 278.1) | 327.2 (217.1, 493.0) | 82.8 (58.3, 117.7) | 167.3 (135.4, 206.7) | < 0.001 |
| 12 months after recruitment | |||||
| Detectable [n (%)] | 56 (100) | 37 (100) | 53 (100) | 146 (100) | |
| Geometric mean (95% CI) (pg/mL) | 868.3 (617.9, 1220.0) | 686.1 (505.4, 931.5) | 320.2 (228.9, 448.1) | 569.5 (464.5, 698.2) | < 0.001 |
| p-Valuec | < 0.001 | 0.013 | < 0.001 | < 0.001 | |
| aDetectable refers to AF-alb > 3 pg/mg and UFB1 > 20 pg/mL. bp-Value for comparing concentrations among villages. cp-Value for comparing concentrations among sampling times in the specified village. | |||||