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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Alcohol. 2014 Dec 17;49(1):37–46. doi: 10.1016/j.alcohol.2014.11.005

Figure 2. S(-)- baclofen increases binge-like ethanol intake.

Figure 2

A) Acquisition of ethanol and saccharin intake. B) The S(-)- baclofen enantiomer increased total binge-like ethanol intake in B6 mice at the 10 mg/kg dose. C) The effect on intake was specific to the second hour of consumption, with the 3 mg/kg and 10 mg/kg dose increasing intake. D) Dose effects on intakes were not reflected in BECs. E) S(-)- baclofen did not alter total saccharin intake. F) S(-)-baclofen did not alter hourly saccharin intake. Mean ± SEM is depicted. Asterisk (*) indicates different than 0 mg/kg at p < .05. Group n's for panels A-C = 12-13. Group n's for panel D and E = 10.