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. Author manuscript; available in PMC: 2015 Feb 3.
Published in final edited form as: Alcohol. 2014 Nov 3;49(1):21–27. doi: 10.1016/j.alcohol.2014.07.017

Figure 4.

Figure 4

CIE exposure and 7 day withdrawal increases long, thin spines on basal dendrites of layer II/III neurons in the lateral OFC. (A) Representative images of control (top) and CIE (bottom) dendrite segments and filament from Figure 2C showing classified spines. (B) Long spine density was significantly increased as a result of CIE exposure and 7 day withdrawal [F(1,7) = 7.20, *p < 0.05]. (C–F) There was no effect of CIE exposure and 7 day withdrawal on spine length, volume, terminal point diameter or mushroom head volume (p > 0.05 for all analyses).