. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: Int J Cancer. 2014 Aug 22;136(7):1688–1696. doi: 10.1002/ijc.29132

Table 2.

Time course and extent of maximum increase in normal brain and U251 glioma pO₂ prior to, during and post carbogen inhalation on 5 consecutive days in mice

Days	Site	pO_{2 base} (mmHg)	PO_{2 max} (mmHg)	T _max (min)	T _base (min)
1	CLB	57.2±4.9	170.5±26.4^‡	17.6±0.8	12.6±0.6
	U251	21.9±3.7^§§	53.6±10.9^†	20.1±1.6	14.1±0.4
2	CLB	59.3±5.7	191.4±41.0^‡	18.4±1.6	12.6±0.8
	U251	18.4±3.9^§§	45.9±9.2^‡	21.7±2.1	14.0±2.4
3	CLB	62.2±6.6	168.6±37.5^‡	18.7±0.8	12.6±0.8
	U251	15.6±2.1^§§^£	45.1±10.7^‡	19.6±1.3	12.4±0.8
4	CLB	52.0±5.1	136.9±31.4^‡	18.9±1.6	13.5±1.3
	U251	13.0±2.1^§§^£	29.7±7.8^‡	22.3±1.1	13.2±0.7
5	CLB	67.0±3.2	119.2±43.4^†	16.8±2.7	13.9±0.9
	U251	14.1±2.4^§	34.5±7.2^†	21.2±1.4	11.9±0.8

Abbreviations: pO₂ base: baseline pO₂; T _max: time to reach maximum pO₂; pO_{2 max}: maximum pO₂; T _base: time to return to the baseline pO₂, the numbers in the brackets are actual time to return to baseline level since switch carbogen to 30%O₂. CLB: Contralateral brain; U251: U251 glioma.

^†

p<0.05,

^‡

p< 0.01, compared with the pO_{2 max} from pO₂ base on same day;

^§

p<0.05,

^§§

p < 0.01, compared with CLB on same day;

^£

p<0.05, compared with the U251 pO₂ on day 1.