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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Magn Reson Med. 2014 Dec 16;73(2):488–496. doi: 10.1002/mrm.25567

Figure 3.

Figure 3

Phantom Experiments for 3 CEST agents with different Δω and exchange rates. a. Z-spectra acquired only using 1/8 time of that for conventional method. b. QUEST dataset for SA (1) with different FA comparing with a single readout. For compound 1, the fits were performed assuming a single readout with QUEST determined rates: ksw_single = 620 s−1, ksw_θ=10° = 630 s−1, ksw_ θ= 20° = 660 s−1, ksw_θ=30° = 520 s−1 (above 15% error). c. QUEST dataset for 5-Chloro-2-(methyl-sulfonamido) benzoic acid (2) with different FA compared with a single readout. For compound 2, QUEST determined rates: ksw_single = 940 s−1, ksw_θ=10° = 980 s−1, ksw _θ= 20° = 940 s−1, ksw _θ= 30° = 1800 s−1 (above 15% error). d. QUEST dataset for glucose (3) with different FA compared with a single readout, showing a pronounced contrast decay when n>5, even for FA = 10°.