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. Author manuscript; available in PMC: 2016 Feb 15.
Published in final edited form as: Dev Biol. 2014 Dec 16;398(2):255–266. doi: 10.1016/j.ydbio.2014.12.008

Fig. 1. The Corset or Dumbbell phenotype.

Fig. 1

(A) sv3 heterozygous larvae develop normally and do not show molting defects. (B,C) A similarly staged sv3 homozygote that has failed to shed the old cuticle from the middle section (corset phenotype) is shown (B) along with a schematic representation of a worm with a constricted middle section (C), in which the gray lines indicate unshed old cuticle. (D-F) In contrast, the corset defect is less frequently seen with other mutations that affect the completion of molting such as dab-1(gk291). Pictured are images of dab-1(gk291) mutants in which the larva has a narrow constriction only (D; black arrowheads), is completely enclosed in old cuticle (E; black arrow indicates unshed cuticle in head region), or has failed to completely shed the old cuticle from the tail (F; white arrow). Black scale bars = 50 µm; white scale bars = 100 µm.