Fig. 3.
Mice immunized with inactivated WSN-Aβ1–10 generated equally strong virus-specific T cell response regardless of presence of virus-specific memory T cells. (A, B) Number of IFNγ producing T cells (A) and proliferation rate of T cells (B) detected in splenocyte cultures of mice primed with inactivated WSN-WT and then rested for three months. (C, D) Number of IFNγ producing T cells (C) and proliferation rate of T cells (D) detected in splenocyte cultures of mice primed with inactivated WSN-WT and then boosted with inactivated chimeric virus after three months of resting period. Error bars represent average ± SD (n=4/group for A and B, and n=7/group for C and D, ***P<0.001).