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. 2015 Jan 12;35(3):675–683. doi: 10.3892/ijmm.2015.2065

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Copyright © 2015, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Immunohistochemical detection of S100P protein expression in placenta and colon tissue. (A) Trophoblasts lining the placental chorionic villi demonstrated uniform and strong staining (magnification, ×200). (B) Normal colonic mucosa showed negative staining (magnification, ×200). (C) Glands with low-grade dysplasia showed heterogeneous nuclear staining and weak cytoplasmic staining (magnification, ×200). (D) Strong nuclear and moderate cytoplasmic staining in glands with high-grade dysplasia (magnification, ×400). (E) Strong staining in the apical region of cytoplasm without nuclear expression (magnification, ×100). (F) Neutrophils forming abscess around invasive cancer displayed very strong immunostaining (magnification, ×200).