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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Genomics. 2014 Nov 28;105(2):108–115. doi: 10.1016/j.ygeno.2014.11.007

Fig. 1. Alternative promoters and protein isoforms of mouse Aebp2.

Fig. 1

A) The alternative transcripts driven by the three promoters (P1-3) of mouse Aebp2 are predicted to produce two protein isoforms. The untranslated and translated regions are marked with open and filled boxes, respectively. The 32 kDa protein (Aebp2-e) includes a zinc finger domain and a basic domain, while the 52 kDa protein (Aebp2-S) includes an additional acidic and neutral domain along with the zinc finger and basic domains. The transcription start sties (TSSs) are marked with arrows. B) The genomic structure of the three promoters of mouse Aebp2. The relative positions of the three promoters are presented along with their sequence conservation levels among different vertebrates. The P1 promoter is rodent-specific whereas the P2 promoter is conserved throughout all vertebrates. The P3 promoter is also conserved among placental mammals.