Table III.

Demographic and clinical information of the primary alloimmunized recipients vs. all other recipients in this study.

Parameter	Primary anti-D formers	All other recipients	p value
Number of recipients (%)	7 (1.4)	478 (98.6)	NC
Gender (Male/Female)	4/3	299/179	0.2
Median age (range), years	60 (2-100)	65 (39-85)	0.2
ABO group (O/A/B/AB)	3/3/1/0	206/212/43/17	0.9
Main diagnosis (haematology-oncology/others)	3/4	264/214	0.5
Iatrogenic immunosuppression (yes/no/unknown)	3/3/1	197/177/104	0.9
History of pregnancy (yes/no)*	2/0	55/12	0.5
Patient location: Europe/Americas	2/5	222/256	0.6
Previous RBC transfusion (yes/no)	6/1	217/261	0.08
Previous PC transfusion (yes/no)	2/5	94/384	0.9
Transfused PCs (whole blood/apheresis/both)	2/4/1	179/288/71	0.8
Median length of serological follow-up (range), days	216 (32-368)	75 (28-2111)	0.09

RBC, red blood cell; PC, platelet concentrate; NC, Not calculated

^*For those whose pregnancy history was known