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. Author manuscript; available in PMC: 2016 Feb 2.
Published in final edited form as: Mol Pharm. 2015 Jan 15;12(2):621–629. doi: 10.1021/mp5006883

Figure 6. DNA transfection levels of both PEI and P(SiDAAr)5P3 luc-DNA-co-s-siRNA polyplexes in MCF-7 and MCF-7/Adr cells.

Figure 6

(A) In MCF-7 cell line, P(SiDAAr)5P3 polyplexes achieved a significantly higher transfection level than PEI polyplexes with the same composition. (B) In MCF-7/Adr cell line, PEI polyplexes achieved significantly higher transfection levels than P(SiDAAr)5P3 polyplexes with the same composition. siRNA incorporation significantly enhanced DNA transfection levels in both cell lines. †: statistically significant compared to PEI polyplexes of the same composition. Data as mean ± standard deviation (n=2). *, † p≤0.05; **, †† p≤0.01; ***, ††† p≤0.001.