Figure 7.
Components of HPA axis impacted by Cre lines in this study. (A) Nkx2.1-Cre-mediated recombination is observed in most of the hypothalamus and posterior pituitary, but not in the PVH (or anterior pituitary). (B) Sim1-Cre-mediated recombination is observed in most neuronal subpopulations in the PVH, including AVP and CRH neurons. (C) Agrp-Cre-mediated recombination is restricted to a subpopulation of neurons in the ARH.