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. 2015 Feb;135(2):395–406.e7. doi: 10.1016/j.jaci.2014.08.027

Fig 1.

Fig 1

Images are shown at ×200 magnification. A-D, Examples of DP2 expression (brown staining) on epithelial cells and inflammatory cells within the bronchial submucosa in rabbit immunoglobulin fraction negative control demonstrating a lack of any positive staining (Fig 1, A), a healthy control subject (Fig 1, B), a patient with mild asthma (Fig 1, C), and a patient with severe asthma (Fig 1, D). E, Dot plot of DP2+ inflammatory cells within the submucosa of healthy control subjects and patients with mild, moderate, and severe asthma. P values are based on the Kruskal-Wallis test. Overall P < .001. P values shown in the figure are based on the Dunn post hoc test. F, Numbers of DP2+ mast cells (mast cell tryptase positive), eosinophils (major basic protein positive), and T cells (CD3+), as assessed by means of colocalization of sequential sections. P values are based on 2-way ANOVA. Overall P < .001. P values shown in the figure based on the Tukey post hoc test. G, Dot plot of DP2+ epithelial cells in healthy control subjects and patients with moderate and severe asthma. P values are based on the Kruskal-Wallis test. Overall P < .001. P values shown in the figure are based on the Dunn post hoc test.