Table 4.
Prevalence Ratios and 95% CIs for Adverse Health Outcomes by Chronic Condition Status
| Variable | General Health |
Mental Health |
Functional Health |
Activity Limitation |
Cancer-Related Pain |
Cancer-Related Anxiety |
Any Adverse Health Status Domain |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PR | 95% CI | PR | 95% CI | PR | 95% CI | PR | 95% CI | PR | 95% CI | PR | 95% CI | PR | 95% CI | |
| Any versus no chronic condition, grade 3-4* | 2.39 | 2.17 to 2.64 | 1.78 | 1.63 to 1.95 | 3.25 | 2.97 to 3.55 | 3.20 | 2.91 to 3.53 | 2.41 | 2.15 to 2.69 | 1.56 | 1.42 to 1.72 | 2.37 | 2.21 to 2.54 |
| One versus no chronic condition, grade 3-4* | 1.96 | 1.76 to 2.19 | 1.53 | 1.38 to 1.69 | 2.62 | 2.38 to 2.89 | 2.53 | 2.28 to 2.82 | 2.25 | 1.99 to 2.55 | 1.41 | 1.26 to 1.57 | 1.99 | 1.85 to 2.15 |
| Two or more versus no chronic conditions, grade 3-4* | 3.80 | 3.33 to 4.34 | 2.63 | 2.32 to 2.98 | 5.45 | 4.81 to 6.17 | 5.41 | 4.75 to 6.16 | 2.87 | 2.45 to 3.37 | 2.03 | 1.76 to 2.34 | 3.95 | 3.53 to 4.42 |
| Organ system-specific versus no organ-specific chronic condition, grade 3-4* | ||||||||||||||
| Second malignancy | 1.80 | 1.49 to 2.19 | 1.22 | 1.01 to 1.46 | 1.54 | 1.28 to 1.84 | 1.45 | 1.20 to 1.76 | 1.29 | 1.03 to 1.63 | 1.70 | 1.41 to 2.05 | 1.55 | 1.33 to 1.80 |
| Vision/hearing/speech | 1.69 | 1.44 to 1.98 | 1.47 | 1.26 to 1.70 | 2.56 | 2.23 to 2.95 | 1.42 | 1.21 to 1.66 | 1.35 | 1.12 to 1.64 | 1.15 | 0.97 to 1.37 | 1.77 | 1.56 to 2.01 |
| Endocrine | 1.24 | 1.05 to 1.45 | 1.41 | 1.23 to 1.62 | 1.11 | 0.96 to 1.29 | 1.17 | 1.00 to 1.37 | 1.26 | 1.05 to 1.52 | 1.24 | 1.06 to 1.46 | 1.30 | 1.16 to 1.46 |
| Respiratory | 3.10 | 2.25 to 4.28 | 2.63 | 1.83 to 3.78 | 2.42 | 1.72 to 3.41 | 3.14 | 2.19 to 4.50 | 2.57 | 1.69 to 3.91 | 2.14 | 1.44 to 3.17 | 2.46 | 1.70 to 3.56 |
| Cardiac | 2.72 | 2.30 to 3.21 | 1.72 | 1.47 to 2.03 | 2.36 | 2.00 to 2.79 | 2.89 | 2.45 to 3.41 | 1.31 | 1.06 to 1.62 | 1.23 | 1.01 to 1.50 | 2.41 | 2.07 to 2.80 |
| Gastrointestinal | 1.44 | 1.13 to 1.84 | 1.29 | 1.04 to 1.61 | 1.29 | 1.03 to 1.61 | 1.41 | 1.10 to 1.81 | 1.30 | 0.98 to 1.71 | 1.48 | 1.17 to 1.87 | 1.34 | 1.13 to 1.60 |
| Renal | 1.78 | 1.16 to 2.74 | 1.55 | 1.02 to 2.35 | 1.94 | 1.21 to 3.11 | 1.77 | 1.11 to 2.83 | 1.09 | 0.61 to 1.94 | 0.98 | 0.55 to 1.75 | 1.77 | 1.15 to 2.74 |
| Musculoskeletal | 1.15 | 0.96 to 1.37 | 1.05 | 0.89 to 1.25 | 1.90 | 1.63 to 2.22 | 3.55 | 3.05 to 4.14 | 3.20 | 2.71 to 3.78 | 1.10 | 0.91 to 1.32 | 2.08 | 1.82 to 2.37 |
| Neurologic | 2.19 | 1.82 to 2.62 | 2.13 | 1.81 to 2.52 | 5.30 | 4.46 to 6.30 | 4.31 | 3.62 to 5.13 | 2.48 | 2.02 to 3.05 | 1.59 | 1.33 to 1.92 | 3.78 | 3.17 to 4.49 |
| Other hematologic† | 1.49 | 1.18 to 1.87 | 1.30 | 1.04 to 1.63 | 1.52 | 1.21 to 1.91 | 1.46 | 1.16 to 1.82 | 1.39 | 1.07 to 1.81 | 1.21 | 0.95 to 1.55 | 1.57 | 1.30 to 1.88 |
Abbreviation: PR, prevalence ratio.
*
Chronic conditions according to the Common Terminology Criteria for Adverse Events, version 4.0.
†
Includes blot clots and aplastic anemia; all generalized estimating equations adjusted for sex, race/ethnicity, age at questionnaire administration, age at diagnosis, body mass index, smoking status, physical activity level, and within-person correlation.