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. 2015 Feb 3;5:8202. doi: 10.1038/srep08202

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(a) Flubendazole IC₉₀ values in control cell lines and neuroblastoma cells transduced with lentiviral vectors encoding for shRNA directed against p53 (p53shRNA) or scrambled, non-targeting shRNA (scr-shRNA). * P < 0.05 relative to non-transduced cell line; (b) Viability of p53 wild-type UKF-NB-3 cells, p53-mutated UKF-NB-3^rVCR¹⁰cells, UKF-NB-3 cells transduced with a lentiviral vector encoding scrambled, non-targeting shRNA (scr-shRNA), or UKF-NB-3 cells transduced with a lentiviral vector encoding shRNA directed against p53 (p53shRNA) after treatment with flubendazole (Flu), nutlin-3 (Nut, μM), or their combination as indicated by MTT assay after 5 day incubation. * P < 0.05 relative to either single treatment, n.d. = not detectable.