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. 2015 Jan 27;15:7. doi: 10.1186/s12861-015-0058-9

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© De Silva et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Heat maps of transcriptional changes in HR+ during early pregnancy. (A) Heat map of Illumina gene probes generated by GenePattern software showing transcriptional changes during early pregnancy. (B-C) Heat maps generated with an input of the 25 most up-regulated and 25 most down-regulated genes in each category based on the values of their Pi scores (see Methods). Twenty-five gene probe sets that are induced (B) and reduced (C) most strongly in HR+ cells specifically at day 3 of pregnancy. (D-E) Gene probe sets that are most strongly induced (D) and reduced (E) in early pregnancy. (F-G) Gene probe sets that are induced (F) and reduced (G) most strongly in HR+ cells specifically at day 7 of pregnancy.