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. 2015 Jan 29;8:6. doi: 10.1186/s13041-015-0096-z

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© Tiwari et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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CSPalpha protein expression is reduced in Alzheimer’s disease superior temporal gyrus. (A) CSPalpha expression in post-mortem STG from patients with severe Alzheimer’s disease (n = 13; average age at death = 73.2 ± 3.4 years) and control subjects (n = 12; average age at death = 76.9 ± 2.1 years). CSPalpha expression was normalized against NSE. (B) The same samples as in panel (A) were used but CSPalpha expression was normalized against synaptophysin (severe Alzheimer’s disease, n = 13; control, n = 12). Panel (C) shows the representative western blots for 5 controls and 5 patients with severe AD. Means ± s.e.m. are shown. **, p < 0.01; ***, p < 0.001.