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Effect of bupropion on carrageenan induced paw edema in rats. Bupropion (10, 20 and 40 mg/kg), indomethacin (10 mg/kg) and the vehicle were administrated 30 min prior to carrageenan (1%) injection, and the rats were evaluated for paw edema 4 h post-carrageenan injection. The values represent the mean variation in the paw volume ± SEM. **P<0.01; ***P<0.001 compared with control group.
