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Effect of bupropion on croton oil induced ear edema in mice. Ear edema was measured at 6 h after croton oil treatment. Bup (bupropion, 10, 20 and 40 mg/kg) and indomethacin (10 mg/kg) and the vehicle were administrated 30 min prior to croton oil application. Each bar represents the mean ± SEM. ***P<0.001 compared with control group.
