Table 1.

Acronym definitions

CC	corpus callosum
CCA	total cross-sectional area of the CC (mm2)
rCCA	time rate of change of CCA: ΔCCA/Δt (mm2/y)
CCP	perimeter of the CC
CIR	CC circularity: 4π × CCA/CCP2 (unitless)
rCIR	time rate of change of CIR: ΔCIR/Δt (yr−1)
CCi	area of CC sub-regions i (i = 1,2,3,4,5)
rCCi	rate of change of CCi (mm2/y)
AD	Alzheimer's disease
OASIS	open access series of imaging studies database
CDR	clinical dementia rating
NC	normal control subjects (CDR = 0)
AD-VM	subjects with very mild AD-type dementia (CDR = 0.5)
AD-M	subjects with mild AD-type dementia (CDR =1)
MRI	magnetic resonance imaging
MP-RAGE	magnetization prepared rapid gradient echo
TR	repetition time
TE	echo time
TD	delay time
TI	inversion time
AC	anterior commissure
PC	posterior commissure
MSP	mid-sagittal plane
DWI	diffusion-weighted imaging
nWBV	normalized whole brain volume