Table III.
Genotype frequencies of three SNPs of IL-17A and IL-17F in gastric cancer patients and controls.
| Cases (n=572) | Controls (n=572) | OR (95% CI) | ||||||
|---|---|---|---|---|---|---|---|---|
|
|
|
|
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| Genotype | n | % | n | % | Hardy-Weinberg equilibrium | Codominant model | Dominant model | Recessive model |
| rs2275913 | ||||||||
| GG | 239 | 41.8 | 260 | 45.4 | Ref. (1.0) | |||
| GA | 250 | 43.7 | 241 | 42.1 | 1.13 (0.87–1.46) | |||
| AA | 83 | 14.5 | 72 | 12.5 | 0.17 | 1.25 (0.86–1.83) | 1.16 (0.91–1.47) | 1.18 (0.83–1.68) |
| rs763780 | ||||||||
| CC | 420 | 73.5 | 472 | 82.5 | Ref. (1.0) | |||
| CT | 67 | 11.7 | 58 | 10.2 | 1.30 (0.88–1.93) | |||
| TT | 85 | 14.8 | 42 | 7.3 | 0.09 | 2.27 (1.51–3.45) | 1.71 (1.27–2.30) | 2.20 (1.47–3.34) |
| rs3748067 | ||||||||
| TT | 460 | 80.4 | 458 | 80.4 | Ref. (1.0) | |||
| TC | 70 | 12.2 | 66 | 11.5 | 1.06 (0.72–1.54) | |||
| CC | 42 | 7.4 | 47 | 8.1 | <0.001 | 0.89 (0.56–1.41) | 0.99 (0.90–1.69) | 0.90 (0.57–1.42) |
SNP, single nucleotide polymorphism; IL, interleukin; OR, odds ratio; CI, confidence interval; Ref. the GG genotype is the reference for the GA genotype.