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. 2015 Feb 3;9:43. doi: 10.3389/fnhum.2015.00043

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Copyright © 2015 Dipasquale, Griffanti, Clerici, Nemni, Baselli and Baglio.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Between-group differences in resting-state network (RSN) spatial maps. Group-level ICA spatial maps of the RSNs (red–yellow) at low (A) and high (B) dimensionality are overlaid with clusters showing significantly lower (blue) functional connectivity in patients with Alzheimer’s disease (AD) relative to healthy controls (HC). Images are shown in radiological orientation. PCC, posterior cingulate cortex; PCC₁, subnetwork 1 of the PCC; mPFC₂, subnetwork 2 of the medial prefrontal cortex; SMN₂, subnetwork 2 of the sensory-motor network.