Table II.
Association between methylated NDRG4 gene expression and clinicopathological parameters of colorectal cancer.
| Tissue | Stool | Urine | Blood | ||||||
|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|
||||||
| Object | Total | Methylated | Unmethylated | Methylation | Unmethylation | Methylated | Unmethylated | Methylated | Unmethylated |
| Age, years | |||||||||
| <65 | 36 | 29 | 7 | 26 | 10 | 25 | 11 | 19 | 17 |
| ≥65 | 48 | 39 | 9 | 38 | 10 | 36 | 12 | 27 | 21 |
| Differentiation | |||||||||
| High-middle | 57 | 49 | 8 | 45 | 12 | 44 | 13 | 29 | 28 |
| Low | 27 | 19 | 8 | 19 | 8 | 17 | 10 | 17 | 10 |
| Lymph node metastasis | |||||||||
| Exist | 55 | 50 | 5a | 48 | 7a | 42 | 13 | 30 | 25 |
| None | 29 | 18 | 11 | 16 | 13 | 19 | 10 | 16 | 13 |
| TNM stage | |||||||||
| I–II | 48 | 42 | 6 | 39 | 9 | 34 | 14 | 26 | 22 |
| III–IV | 36 | 26 | 10 | 25 | 11 | 27 | 9 | 20 | 16 |
a
P<0.05.
TNM, TNM Classification of Malignant Tumors cancer staging system (36).