Table 1.
Orientia tsutsugamushi Ikeda strain Anks.
| Ank | Gene | Chromosomal coordinatesa | Number of ankyrin repeats | Amino acid locations of ankyrin repeats per Ank protein |
|---|---|---|---|---|
| Ank1_01 | OTT_0036 | (+) 44402–44929 | 0b | |
| Ank1_02 | OTT_0753 | (−) 780290–781279 | 3 | 23–52, 56–85, 89–118 |
| Ank2 | OTT_0049 | (−) 54830–55864 | 4 | 1–30, 38–67, 71–100, 104–134 |
| Ank3_01 | OTT_0153 | (−) 144257–144901 | 6 | 6–36, 40–69, 73–115, 119–149, 153–182, 186–213 |
| Ank3_02c | OTT_0236 | (−) 223718–224077 | 3 | 5–47, 51–81, 85–114 |
| Ank3_03c | OTT_0237 | (−) 224310–224588 | 2 | 12–42, 46–75 |
| Ank3_04 | OTT_0288 | (−) 289650–290294 | 6 | 6–36, 40–69, 73–115, 119–149, 153–182, 186–213 |
| Ank3_05 | OTT_0316 | (+) 329027-329575 | 5 | 8–37, 41–83, 87–117, 121–150, 154–181 |
| Ank3_06 | OTT_0982 | (+) 1032433–1032981 | 5 | 8–37, 41–83, 87–117, 121–150, 154–181 |
| Ank3_07c | OTT_1032 | (−) 1072659–1073159 | 4 | 25–67, 71–101, 105–134, 138–165 |
| Ank3_08 | OTT_1112 | (−) 1146364–1147071 | 5 | 6–36, 40–69, 73–115, 119–149, 153–182 |
| Ank3_09 | OTT_1118 | (+) 1152471–1153019 | 5 | 8–37, 41–83, 87–117, 121–150, 154–181 |
| Ank3_10c | OTT_1236 | (−) 1271358–1271513 | 0 | |
| Ank3_11 | OTT_1453 | (−) 1485654–1486298 | 6 | 6–36, 40–69, 73–115, 119–149, 153–182, 186–213 |
| Ank3_12c | OTT_1465 | (+) 1497782–1498282 | 4 | 25–67, 71–101, 105–134, 138–165 |
| Ank3_13 | OTT_1696 | (−) 1721877–1722521 | 6 | 6–36, 40–69, 73–115, 119–149, 153–182, 186–213 |
| Ank3_14c | OTT_1730 | (−) 1751181–1751648 | 4 | 14–56, 60–90, 94–123, 127–154 |
| Ank3_15 | OTT_1852 | (−) 1883248–1883895 | 6 | 7–37, 41–70, 74–116, 120–150, 1540183, 187–214 |
| Ank4_01 | OTT_0210 | (−) 200588–201766 | 7 | 50–79, 83–112, 116–147, 151–180, 184–214, 218–279, 283–315 |
| Ank4_02 | OTT_1916 | (+) 1951498–1952676 | 7 | 50–79, 83–112, 116–147, 151–180, 184–214, 218–279, 283–315 |
| Ank5_01 | OTT_0214 | (+) 205067–206104 | 4 | 2–29, 36–65, 69–99, 103–132 |
| Ank5_02 | OTT_0412 | (+) 432777–433814 | 4 | 2–29, 36–65, 69–99, 103–132 |
| Ank5_03 | OTT_0487 | (−) 505323–506360 | 4 | 2–29, 36–65, 69–99, 103–132 |
| Ank6_01 | OTT_0226 | (−) 215330–216340 | 4 | 23–52, 56–85, 89–118, 122–158 |
| Ank6_02 | OTT_1149 | (+) 1180783–1181793 | 4 | 23–52, 56–85, 89–118, 122–158 |
| Ank6_03 | OTT_1496 | (+) 1525158–1526168 | 4 | 23–52, 56–85, 89–118, 122–158 |
| Ank6_04 | OTT_1912 | (−) 1947492–1948502 | 4 | 23–52, 56–85, 89–118, 122–158 |
| Ank7_01c | OTT_0250 | (−) 241933–242373 | 2 | 35–64, 100–130 |
| Ank7_02 | OTT_1509 | (−) 1535130–1536386 | 3 | 35–64, 68–96, 100–129 |
| Ank7_03 | OTT_1936 | (−) 1969541–1970797 | 3 | 35–64, 68–96, 100–129 |
| Ank8 | OTT_0257 | (−) 252600–253769 | 5 | 1–31, 35–64, 68–98, 111–140, 144–173 |
| Ank9 | OTT_0298 | (+) 307356–308624 | 7 | 21–51, 55–84, 88–117, 121–150, 154–188, 192–221, 225–256 |
| Ank10_01 | OTT_0398 | (−) 416849–418504 | 9 | 20–50, 54–83, 87–117, 121–150, 154–184, 188–217, 222–252, 256–285, 290–319 |
| Ank10_02 | OTT_0875 | (+) 918456–920111 | 9 | 20–50, 54–83, 87–117, 121–150, 154–184, 188–217, 222–252, 256–285, 290–319 |
| Ank10_03c | OTT_1089 | (−) 1122006–1122263 | 0 | |
| Ank10_04c | OTT_1090 | (−) 1122302–1122703 | 2 | 14–43, 48–78 |
| Ank11 | OTT_0459 | (−) 482167–482853 | 2 | 10–39, 132–161 |
| Ank12_01 | OTT_0602 | (−) 621330–622814 | 7 | 35–64, 68–97, 102–144, 148–178, 182–211, 215–246, 250–281 |
| Ank12_02 | OTT_1300 | (−) 1318892–1320379 | 8 | 1–30, 35–64, 68–97, 102–144, 148–178, 182–211, 215–246, 250–281 |
| Ank13 | OTT_0852 | (−) 899766–901238 | 8 | 18–48, 52–81, 85–114, 118–147, 151–182, 186–215, 219–254, 258–285 |
| Ank14 | OTT_1019 | (+) 1063942–1065198 | 5 | 33–62, 66–95, 99–128, 132–161, 162–193 |
| Ank15 | OTT_1232 | (+) 1268108–1269037 | 1 | 105–134 |
| Ank16 | OTT_1271 | (+) 1296255–1297055 | 3 | 5–34, 41–93, 97–125 |
| Ank17 | OTT_1478 | (+) 1505350–1506078 | 4 | 37–66, 69–98, 102–129, 133–163 |
| Ank18d | OTT_1518 | (−) 1548914–1549132 | 0 | |
| Ank19 | OTT_1519 | (−) 1549361–1549852 | 4 | 4–33, 37–75, 79–110, 114–163 |
| Ank20 | OTT_1575 | (+) 1603487–1605013 | 9 | 32–62, 66–96, 101–130, 135–164, 165–194, 200–233, 237–267, 271–300, 304–335 |
a
(+) and (−) refer to the sense and antisense DNA strands, respectively.
b
Ank1_01 is homologous to the non-ankyrin repeat-containing portions of Ank1_02.
c
These ORFs are annotated as probable pseudogenes by Nakayama et al. (2008).
d
Ank18 carries no ankyrin repeats, but exhibits homology to the non-ankyrin repeat portion of its homolog in the O. tsutsugamushi Boryong strain, Ank1u7 (OTBS_1195; Cho et al., 2007).