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Expression of miR-92a in colorectal adenocarcinoma (CA) and its precancerous lesions, revealed by in situ hybridization (magnification, ×200). (A) High-grade intraepithelial neoplasia. (B) Low-grade intraepithelial neoplasia. (C) CA. (D) Normal control of CA. Positive expression of miR-92a is represented by nitro blue tetrazolium/5-bromo-4-chloro-3-indolyl phosphate, with the nuclei counterstained by methylgreen. Scale bar, 100 μm.
