Table 7.
Current investigations in gene therapy
| Gene therapies | Agent | Route of administration | Status | Study ID | Sponsor |
|---|---|---|---|---|---|
| Cytokine-based | Interferon | Intrapleural | Recruiting | NCT01212367 | University of Pennsylvania/NCI |
| Interferon with chemotherapy | Intrapleural | Unknown | NCT01119664 | University of Pennsylvania | |
| Suicide gene | Herpes simplex virus | Intrapleural | Recruiting | NCT01721018 | Virttu Biologics Limited |
| Measles virus | Intrapleural | Recruiting | NCT01503177 | Mayo Clinic/NCI | |
| Autologous modified | Fibroblast activation protein | Intrapleural | Not yet recruiting | NCT01722149 | University of Zurich |
| T-cells with receptor to: | Mesothelin | Intravenous | Recruiting | NCT01355965 | University of Pennsylvania |
Abbreviations: ID, identification number; NCI, National Cancer Institute.