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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Pancreas. 2014 Jul;43(5):708–719. doi: 10.1097/MPA.0000000000000109

Figure 4. Time course of the effect of fractalkine (CX3CL1: 10–100 ng/ml) on various cell signaling cascades (Panel A and B) and comparison with effect of MCP-1 (200 ng/ml) (Panel C).

Figure 4

Results for phospho-ERK, phospho-JNK, phospho-p38, phospho-Akt and phospho-CREB are determined using specific phospho-antibodies. The results are determined at the indicated times with CX3CL1 and MCP-1, and after a 5 min incubation with the positive controls, PDGF-BB (PDGF, top panel) or forskolin (For, bottom panel). This experiment is representative of 4 experiments.