Figure 1.

Activated B cells from tumor-draining lymph nodes (TDLN) mediate tumor regression after adoptive transfer in mice bearing 3-day established lung metastases. In these two separate experiments groups of mice (n=6) received activated T cells alone, B cells alone, or a combination of both. Mean number of pulmonary metastases (±SEM) at the end of the experiments are depicted in the graphs. The combination of T and B cells was superior to all other groups. (From Li et al.)³⁹