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. Author manuscript; available in PMC: 2015 Feb 3.
Published in final edited form as: J Surg Oncol. 2011 Sep 6;105(4):431–435. doi: 10.1002/jso.22093

Figure 2.

Figure 2

Activated B cells from TDLN can cause tumor cell cytolysis in an immunologically specific fashion. 4T1 TDLN B cells were secondarily activated with LPS/anti-CD40 and evaluated for cytotoxicity using an LDH release assay. Activated B cells were admixed with tumor cells at different effector: target (E:T) ratios and the amount of killing was assessed. 4T1 TDLN B cells were able to kill 4T1 tumor cells, and not the irrelevant Renca or TSA tumors as shown in these two separate experiments. (From Li et al.)40