Table 2. Mean difference in log serum concentrations of reproductive hormones according to one-standard-deviation continuous change in stress levela (n=507 cycles).
| Log Hormone | Daily Stress β (95% CI) | PSS-4 (cycle) β (95% CI) | PSS-14 (baseline) β (95% CI) |
|---|---|---|---|
| Estradiol (pg/mL)b | |||
| Follicular | -0.08 (-0.12 to -0.04) | -0.03 (-0.09 to 0.03) | 0.02 (-0.07 to 0.07) |
| Luteal | -0.01 (-0.04 to 0.03) | 0.03 (-0.03 to 0.06) | 0.05 (-0.01 to 0.14) |
| Free Estradiol (pg/mL)b | |||
| Follicular | -0.09 (-0.12 to -0.05) | -0.06 (-0.09 to -0.001) | 0.00 (-0.07 to 0.07) |
| Luteal | 0.00 (-0.08 to 0.07) | 0.01 (-0.03 to 0.03) | 0.03 (-0.02 to 0.14) |
| Progesterone (ng/mL)b | |||
| Luteal | -0.05 (-0.11 to 0.01) | 0.00 (-0.09 to 0.09) | 0.02 (-0.07 to 0.14) |
| FSH (mIU/mL)b | |||
| Follicular | 0.01 (-0.01 to 0.03) | 0.01 (-0.03 to 0.03) | 0.02 (-0.03 to 0.06) |
| Luteal | 0.04 (0.01 to 0.07) | 0.03 (-0.01 to 0.06) | 0.01 (-0.07 to 0.07) |
| LH (ng/mL)b | |||
| Follicular | -0.07 (-0.11 to -0.03) | -0.06 (-0.12 to -0.03) | -0.03 (-0.07 to 0.07) |
| Luteal | 0.03 (-0.01 to 0.07) | 0.01 (-0.06 to 0.06) | -0.06 (-0.14 to 0.01) |
a
Analyses conducted using linear mixed models adjusting for age, race, percent body fat, depression score, and daily vigorous exercise. Overall, there were 3891 (95.9%) measurements of each reproductive hormone collected from up to 16 clinic visits for the 259 women.
b
International System of Units (SI) conversion, estradiol: 1 pg/mL = 3.67 pmol/L; progesterone: 1 ng/mL = 3.18 nmol/L; LH: 1 ng/mL = 4.34 mIU/L; FSH 1 mIU/ml = 1 IU/L.