Fig. 3.

The progression or regression of an HRE in patients with T2DM. In participants who did not have an HRE at baseline, 1 year of exercise and lifestyle intervention attenuated the development of an HRE when compared with a control group (29.8 vs. 59.5% progression to an HRE, p = 0.006). In participants who did have an HRE at baseline, 1 year of lifestyle intervention did not change the HRE status when compared to a control group (22.0 vs. 23.5%, p = 0.855). Reproduced from Schultz et al. [85] with permission from Wolters Kluwer Health.