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. 2015 Feb 3;10(2):e0112305. doi: 10.1371/journal.pone.0112305

Figure 2. The mRNA expression levels of Cosmc.

Figure 2

The mRNA expression levels of Cosmc by RT-PCR. Samples are B lymphocytes from peripheral blood of the 3 groups (IgAN patients, n = 26; other renal disease patients, n = 11; healthy children participants, n = 13). Error bars represent s.e.m. and * * * for p-value ≤ 0.001. (a) Cosmc mRNA expression in 3 groups after 48 hours culturing. (b) Cosmc mRNA expression in 3 groups after 48 hours culturing with IL-4 (10 ng/ml). (c) Cosmc mRNA expression in 3 groups after 48 hours culturing with AZA (1 umol/l). (d) Cosmc mRNA expression in 3 groups treated or not (beige) with IL-4 (green) or AZA (blue). (e, f) Compared to plain medium, IL-4 or AZA caused the alteration of Cosmc mRNA levels in the other two groups. The mRNA data in Figure was the relative quantification of the ratio of Cosmc/GAPDH in each sample.