Fig. 6.
Fibrinogen-α and CD177 expression after cigarette smoke exposure. Mice were treated as described in Fig. 1. Sixteen hours after the last smoke exposure lungs were collected. Microarray analysis on lung homogenates revealed that fibrinogen-α and CD177 were downregulated after smoke exposure in M3R−/− animals receiving wild-type bone marrow cells compared with wild-type animals. Therefore, gene expression of fibrinogen-α (A) and CD177 (B) was determined by real-time qPCR. Results are expressed as means ± SE. *P < 0.05; n = 5–8 animals.