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. 2014 Oct 31;42(2):278–287. doi: 10.1007/s00259-014-2945-x

Table 2.

Tissue distribution of 89Zr after i.v. inoculation of [89Zr]oxinate4-labelled eGFP-5T33 cells in C57Bl/KaLwRij mice

Organ 89Zr-oxine 89Zr-oxine 89Zr-oxine 89Zr-oxine 89Zr-oxine 89Zr-oxine
9 h (n = 3) 9 h (n = 3) 24 h (n = 4) 24 h (n = 4) 48 h (n = 3) 48 h (n = 3)
%ID/g %ID %ID/g %ID %ID/g %ID
Heart 0.85 ± 0.09 0.18 ± 0.02 0.50 ± 0.13 0.09 ± 0.01 0.32 ± 0.07 0.08 ± 0.02
Lungs 2.28 ± 0.41 0.60 ± 0.11 1.35 ± 0.07 0.41 ± 0.04 0.68 ± 0.06 0.21 ± 0.04
Liver 44.6 ± 10.6 73.9 ± 6.3 42.2 ± 9.1 69.2 ± 7.5 30.9 ± 4.2 57.6 ± 5.3
Spleen 75.0 ± 13.1 5.8 ± 0.80 99.5 ± 11.0 6.6 ± 0.38 54.9 ± 1.2 4.7 ± 0.52
Stomach 0.29 ± 0.08 0.14 ± 0.01 0.45 ± 0.17 0.16 ± 0.08 0.28 ± 0.07 0.12 ± 0.01
Small int. 0.35 ± 0.01 0.34 ± 0.05 0.34 ± 0.02 0.28 ± 0.02 0.27 ± 0.07 0.32 ± 0.04
Large int. 0.34 ± 0.04 0.36 ± 0.04 0.27 ± 0.02 0.29 ± 0.14 0.21 ± 0.04 0.26 ± 0.10
Kidneys 3.9 ± 0.45 1.8 ± 0.15 4.0 ± 0.44 1.65 ± 0.26 3.0 ± 0.43 1.42 ± 0.21
Muscle 0.19 ± 0.03 – 0.21 ± 0.05 – 0.13 ± 0.03 –
Femur 7.1 ± 1.4 0.63 ± 0.08 8.4 ± 0.47 0.76 ± 0.02 5.3 ± 0.85 0.52 ± 0.04
Salivary gl. 0.54 ± 0.06 0.12 ± 0.004 0.52 ± 0.14 0.10 ± 0.02 0.44 ± 0.04 0.10 ± 0.03
Blood 1.8 ± 0.18 – 1.0 ± 0.18 – 0.53 ± 0.18 –
Liver:spleen 0.60 ± 0.18 12.7 ± 2.1 0.42 ± 0.10 10.5 ± 1.3 0.56 ± 0.08 12.1 ± 1.7
Liver:femur 6.28 ± 1.94 116.8 ± 17.2 5.02 ± 1.12 91.1 ± 10.2 5.83 ± 1.23 110.8 ± 13.5
Spleen:femur 10.6 ± 2.78 9.2 ± 1.7 11.9 ± 1.47 8.7 ± 0.56 10.4 ± 1.68 9.1 ± 1.22
Liver:kidneys 11.4 ± 3.0 40.9 ± 4.8 10.6 ± 2.6 42.0 ± 8.1 10.3 ± 2.0 40.5 ± 7.1
Spleen:kidneys 19.2 ± 4.0 3.2 ± 0.52 24.9 ± 3.9 4.0 ± 0.67 18.3 ± 2.7 3.3 ± 0.61
Femur:kidneys 1.8 ± 0.42 0.35 ± 0.05 2.1 ± 0.26 0.46 ± 0.07 1.8 ± 0.38 0.37 ± 0.06

%ID and %ID/g were calculated after ex vivo tissue counting; mean ± SD