Table 1. Plasma amino acid concentrations at baseline.
| WT | Spf-j | ||||||
|---|---|---|---|---|---|---|---|
| μM | SD | N | μM | SD | N | P-value | |
| Taurine | 475.1 | 74.8 | 9 | 435.9 | 37.2 | 10 | 0.15 |
| Aspartic Acid | 20.1 | 3.2 | 9 | 19.3 | 3.1 | 10 | 0.58 |
| Hydroxyproline | 17.4 | 8.5 | 9 | 18.0 | 15.3 | 10 | 0.92 |
| Threonine | 219.6 | 19.7 | 9 | 185.4 | 13.5 | 10 | <0.01 |
| Serine | 152.8 | 15.7 | 9 | 147.7 | 14.1 | 10 | 0.46 |
| Asparagine | 45.1 | 8.7 | 9 | 39.6 | 14.0 | 10 | 0.32 |
| Glutamic Acid | 40.2 | 12.3 | 9 | 36.9 | 7.7 | 10 | 0.48 |
| Glutamine | 654.7 | 67.1 | 9 | 768.3 | 28.2 | 10 | <0.01 |
| Proline | 115.7 | 17.4 | 9 | 105.4 | 10.6 | 10 | 0.13 |
| Glycine | 302.1 | 63.7 | 9 | 253.2 | 55.3 | 10 | 0.09 |
| Alanine | 458.1 | 48.8 | 9 | 463.1 | 52.7 | 10 | 0.83 |
| Citrulline | 95.4 | 18.6 | 9 | 39.7 | 20.2 | 10 | <0.01 |
| Valine | 251.6 | 19.5 | 9 | 216.6 | 19.1 | 10 | <0.01 |
| Methionine | 87.7 | 7.9 | 9 | 78.9 | 11.7 | 10 | 0.08 |
| Isoleucine | 99.8 | 12.2 | 9 | 75.3 | 8.2 | 10 | <0.01 |
| Leucine | 153.6 | 35.5 | 9 | 122.6 | 15.6 | 10 | 0.02 |
| Tyrosine | 116.2 | 12.5 | 9 | 106.8 | 13.7 | 10 | 0.14 |
| Phenylalanine | 74.4 | 6.7 | 9 | 68.8 | 8.7 | 10 | 0.14 |
| Homocystine | 0.6 | 0.9 | 9 | 0.1 | 0.3 | 10 | 0.14 |
| Ornithine | 95.3 | 14.0 | 9 | 73.4 | 8.3 | 10 | <0.01 |
| Lysine | 386.4 | 39.5 | 9 | 331.1 | 41.0 | 10 | <0.01 |
| Histidine | 75.4 | 8.0 | 9 | 79.7 | 8.8 | 10 | 0.29 |
| Arginine | 138.4 | 19.8 | 9 | 96.2 | 26.3 | 10 | <0.01 |
Plasma was collected in 8-week-old spf-j and WT and snap frozen until analysis. Amino acid concentrations were determined by an amino acid analyzer and expressed as μmol/L. T-test with P < 0.05.. WT – wild type, SD – standard deviation.