Table 2.

Experimental runs and their observed dependent variables

Run	Factors			Dependent variables
	X1	X2	X3	Y1	Y2	Y3
1	50	90	40	186	66.32	18.7
2	50	80	50	195	63.65	15.5
3	30	70	50	136	57.37	51.2
4	10	70	40	137	89.21	44
5	30	70	30	181	90.74	39
6	30	90	50	183	77.35	29
7	50	80	30	180	55.46	32.6
8	10	80	50	155	94.7	30.7
9	10	80	30	134	91.7	31
10	50	70	40	190	86.38	31.3
11	30	90	30	172	79.72	20.3
12	10	90	40	156	97.05	15.6
13	30	80	40	174	86.5	36.7
14	30	80	40	158	82.5	34.3
15	30	80	40	162	79.9	33.3

Notes: Factors studied were percentage of SMV in the SMV-zein mixture (X₁), ethanol concentration (X₂), and caseinate concentration (X₃). The selected dependent variables were mean particle size (Y₁), SMV encapsulation efficiency (Y₂), and cumulative percentage of drug permeated after 1 hour (Y₃).